March 9, 2016 |Project Tycho® Data Used to Study US and UK Measles Epidemics

periodicityMeasles epidemics continue to pose a significant public health risk wherever vaccination coverage is low. In a paper published in the PLoS Computational Biology, February 2016, researchers used Project Tycho® data to compare 20-year measles incidence time series in 80 major cities during the prevaccination era. Forty of these cities were located in the US and 40 in the UK. Results showed that slight changes in the seasonal pattern of measles transmission caused by differences in the length of school holidays can lead to chaotic patterns, reducing the capacity to forecast epidemics and to determine the efficacy of control strategies.


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The Project Tycho® database is funded by the Bill & Melinda Gates Foundation and the National Institutes of Health

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